Sequencing the Genome of the Domestic Dog Canis familiaris
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“Defense” injuries in attacks on humans by domestic dog (Canis lupus familiaris) and jaguar (Panthera onca)
This communication describes two attacks by domestic and wild carnivores in Caceres County, localized in the Pantanal area, an extensive flooded plain in Mato Grosso State, Midwest region of Brazil. The first attack took place in an urban area and was caused by a Rottweiler dog (Canis lupus familiaris) created by the family of the victim. Another attack occurred in a rural area, caused by a jag...
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The complete nucleotide sequence of the mitochondrial genome of the domestic dog, Canis familiaris, was determined. The length of the sequence was 16,728 bp; however, the length was not absolute due to the variation (heteroplasmy) caused by differing numbers of the repetitive motif, 5'-GTACACGT(A/G)C-3', in the control region. The genome organization, gene contents, and codon usage conformed to...
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UNLABELLED High-throughput genotyping and sequencing technologies facilitate studies of complex genetic traits and provide new research opportunities. The increasing popularity of genome-wide association studies (GWAS) leads to the discovery of new associated loci and a better understanding of the genetic architecture underlying not only diseases, but also other monogenic and complex phenotypes...
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The dog (Canis familiaris) was chosen for sequencing both for its unusual potential for disease gene mapping and for its clear value for mammalian comparative sequence analysis. The current 7.5x assembly generated from a female boxer is of high quality and has already proven useful for identification of regulatory elements . The SNP map accompanying the genome sequence has also been utilized to...
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